Is the study of Gutteridge and Halliwell [44] showing that Na+, K+-ATPase reduces its activity up to 50 due to oxidative stress. The present findings show that the rats exhibited a decrease in the activity of AChE in the unleaded group in comparison with either the control or the leaded groups. In addition to its function in degrading acetylcholine and modulation of neural function; AChE as a str