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The antibodies are involved in release of complement and anaphylatoxins which can cause or exacerbate DHF/DSS. These systems are inextricable and strongly associated with dengue pathogenesis.Dengue Background and SignificanceThe Dengue Virus is a member of the family Flaviviridae along with other noted viruses Yellow Fever, West Nile, and Japanese Encephalitis. Dengue is a positive stranded RNA ar
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D proteins may be processed in transfectedWJV|www.wjgnet.comAugust 12, 2015|VolumeD proteins may be processed in transfectedWJV|www.wjgnet.comAugust 12, 2015|Volume 4|Issue 3|Trovato M et al . Vaccine delivery systemsTable 1 Overview of the different vaccine formulationsVaccine type Live attenuated vaccines Description Advantages Disadvantages Immunogenicity Humoral and cytotoxic immune resp
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Izes DHF/DSS are regulated by Complement proteins and associated anaphylatoxins. These three systems both interact and reinforce each other to create a potentially life threatening situation during a Dengue infection.Antibodies Antibody Dependent Enhancement (ADE) has been proposed to be a mechanism by which the immune system may enhance viral pathogenesis[7]. When monkeys were passively immunized
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Izes DHF/DSS are regulated by Complement proteins and associated anaphylatoxins. These three systems both interact and reinforce each other to create a potentially life threatening situation during a Dengue infection.Antibodies Antibody Dependent Enhancement (ADE) has been proposed to be a mechanism by which the immune system may enhance viral pathogenesis[7]. When monkeys were passively immunized
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That provides selection and propagation in host bacteria. Although the exactThat provides selection and propagation in host bacteria. Although the exact mechanism by which DNA vaccines work still remains unclear recent advances have provided a deeper , understanding of the molecular and immunological [12-14] mechanisms of action of these vectors . Generally, once the DNA plasmid is administe
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